Sistine Chapel ceiling (Michelangelo)
Must-SeeThe most famous ceiling in the world. 500 square metres of biblical scenes. Visit first thing in the morning for any chance of contemplation.
Scrovegni Chapel (Giotto)
Must-See38 scenes that launched modern painting. Book ahead — 15-minute timed visits in climate-controlled groups.
Brancacci Chapel (Masaccio)
Must-SeeThe Expulsion from Eden — raw emotion in wet plaster. The frescoes that taught Michelangelo and Leonardo.
Last Supper (Leonardo)
Must-SeeNot true fresco (Leonardo experimented) — hence the deterioration. Book 2-3 months ahead. 15-minute visits.
Raphael Rooms, Vatican
Must-SeeFour rooms of Raphael frescoes including the School of Athens. Often rushed through on the way to the Sistine — slow down here.
Where to start
Italy has the world's greatest concentration of frescoes. Use this guide to find the masterpieces — then let yourself be surprised by what you discover on your own.