Separate wing from the Sistine route. 95% walk past. Inside: Raphael's Transfiguration (1520, his last, unfinished at death at 37). Caravaggio's Deposition (Christ lowered from the cross, the slab projecting toward you). Leonardo's St. Jerome (unfinished, raw genius). Same ticket as Vatican Museums.
Strategy: Enter Vatican Museums → turn RIGHT immediately → Pinacoteca (30 min, empty) → THEN Sistine flow. Room VIII Raphael. Room XII Caravaggio. Room IX Leonardo. Full Vatican strategy →